Publications

2020

Zhang S*, Zhang H*, Zhou Y*, Qiao M*, Zhao S* et al. Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants. Science 2020; 369: 561–565. * co-first author

2019

Zhao S, Liu J, Nanga P et al. Detailed modeling of positive selection improves detection of cancer driver genes. Nature communications 2019; 10: 1–13. 13

Zammataro L, Lopez S, Bellone S et al. Whole-exome sequencing of cervical carcinomas identifies activating erbb2 and pik3ca mutations as targets for combination therapy. Proceedings of the National Academy of Sciences 2019; 116: 22730–22736. 14

2018

Ward MC, Zhao S, Luo K et al. Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs. Elife 2018; 7: e33084.

Liu Y, Liang Y, Cicek AE et al. A statistical framework for mapping risk genes from de novo mutations in whole-genome-sequencing studies. The American Journal of Human Genetics 2018; 102: 1031–1047.

2016

Zhao S, Bellone S, Lopez S et al. Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial–mesenchymal transition. Proceedings of the National Academy of Sciences 2016; 113: 12238–12243.

Bi M, Zhao S, Said JW et al. Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma. Proceedings of the National Academy of Sciences 2016; 113: 2170–2175.

Cocco E, Lopez S, Black J et al. Dual ccne1/pik3ca targeting is synergistic in ccne1-amplified/pik3ca-mutated uterine serous carcinomas in vitro and in vivo. British journal of cancer 2016; 115: 303–311.

2014

Zhao S, Choi M, Heuck C et al. Serial exome analysis of disease progression in premalignant gammopathies. Leukemia 2014; 28: 1548–1552

2013

Zhao S, Choi M, Overton JD et al. Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma. Proceedings of the National Academy of Sciences 2013; 110: 2916–2921.